Synaptic pathology and glial responses to neuronal injury precede the formation of senile plaques and amyloid deposits in Clark, HB, Barnes, DL, O''Brien, TD, Johnson, KH. A betaassociated cerebral angiopathy and senile plaques DA, Poon, HF. The senescenceaccelerated prone mouse (SAMP8): a model of agerelated cognitive decline with